U-698-M

Cat.No.: CSC-C0101

Species: Human

Source: B cell lymphoma

Morphology: single or clumped cells in suspension; some cells adhere to plastic

Culture Properties: suspension

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Cat.No.

CSC-C0101

Description

Established from the involved tonsil of a 7-year-old boy with lymphoblastic lymphoma at diagnosis prior to therapy in 1972; cells were described to be EBV-negative

Species

Human

Source

B cell lymphoma

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

suspension

Morphology

single or clumped cells in suspension; some cells adhere to plastic

Karyotype

Human hyperdiploid karyotype with 5.5% polyploidy - 49(44-50)<2n>XY, +3, +7, -14, +mar, dup(1)(q43q21.2), der(2)t(2;3)(p16;p11), add(3)(p11), del(6)(q15q22), del(9)(p22), dup(11)(q23q13), add(13)(p12), add(16)(q24) - carries large submetacentric dup(1) ma

Quality Control

Mycoplasma: negative in DAPI, microbiological culture assays
Immunology: CD3 -, CD10 +, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, CD138 -, HLA-DR +, sm/cyIgG -, sm/cyIgM +, sm/cykappa +, sm/cylambda -
Viruses: ELISA: reverse transcriptase negative;

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 6 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

What kills tumor cells?

Oncolytic viruses kill individual cancer cells, but studies also suggest that they can boost the immune system's ability to recognize and kill a tumor. The viruses enter tumor cells specifically and replicate, eventually breaking the cells apart.

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