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TEL/AML1 Translocation, Dual Fusion Probe
- Specification
Cat.No.
FHPC-098
Description
The TEL/AML1 fusion gene is brought about by the cytogenetically invisible t(12;21) translocation. The rearrangement is the most common in childhood B-ALL and has been detected using FISH in around 21% of cases, compared to a pick-up rate of 0.05% by conventional cytogenetics. The translocation is associated with a favourable outcome though it has also been implicated with late relapse. Both the TEL1 and AML1 genes encode transcription factors but TEL1 has been shown to be required specifically for completing transcription during haematopoiesis within bone marrow.
Size
5 Tests, 10 Tests
Label
Red/Green
Specificity
Human
Locus
t(12;21)
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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