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ROS1 Break Probe
- Specification
Cat.No.
FONC-107
Description
The receptor tyrosine kinase c-ros oncogene (ROS1) is an orphan receptor tyrosine kinase of the insulin receptor family and is located at 6q22. ROS1 consists of a large extracellular domain that is composed of six fibronectin repeats, a transmembrane domain, and an intracellular kinase domain. ROS1 rearrangement has been described to define a molecular subset of Non Small-Cell Lung Cancer (NSCLC).
The ROS1 (6q22) Break Probe is optimized to detect translocations involving the ROS1 gene region at the 6q22 locus, as well as the 240 kb deletion forming the ROS1‐GOPC fusion gene, in a dualcolor assay on formalin‐fixed paraffin‐embedded tissue samples.
Size
10 Tests
Label
Red/Green
Locus
6q22
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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