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PAX3 Breakapart Probe
- Specification
Cat.No.
FONC-096
Description
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children. One of the primary histological subtypes is the alveolar RMS (ARMS). The majority (80%) of ARMS are associated with the t(2;13)(q35;q14) translocation and less commonly with t(1;13)(p36;q14), leading to the fusion of transcription factor FHKR or FOXO1 to the transcription factors PAX3 and PAX7 respectively.In cases of ARMS which is negative for FKHR translocation, two variant PAX3 translocation associated fusion transcripts (PAX3-AFX and PAX3-NCOA1) could be present.
Size
5 Tests, 10 Tests
Label
Red/Green
Locus
2q35/13q14
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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