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N-MYC/LAF Amplification Probe
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Cat.No.
FONC-089
Description
The proto-oncogene N-MYC; a transcription factor which plays a role in regulation of cell growth and proliferation, is mainly expressed in the developing nervous system and is critical during neural crest embryogenesis. Overexpression of N-MYC seems to block differentiation and increase cell proliferation, this is the most important unfavourable prognostic factor for neuroblastoma and it is amplified in 25% of cases. Neuroblastoma is a dominating group of neuron tumours and is one of the most common solid tumours in children.
Size
5 Tests, 10 Tests
Label
Red/Green
Specificity
Human
Locus
2q
Usage

Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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