JURL-MK2

Cat.No.: CSC-C0541

Species: Human

Source: chronic myeloid leukemia in blast crisis

Morphology: round single cells growing in suspension, heterogenous in size, occasional giant cells

Culture Properties: suspension

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Cat.No.

CSC-C0541

Description

Established from the peripheral blood of a 73-year-old man with chronic myeloid leukemia (CML) in blast crisis in 1993; cells carry the Philadelphia chromosome; JURL-MK1 and JURL-MK2 are sister cell lines derived from the same patient

Species

Human

Source

chronic myeloid leukemia in blast crisis

Recommended Medium

85% RPMI-1640 + 15% h.i. FBS

Culture Properties

suspension

Morphology

round single cells growing in suspension, heterogenous in size, occasional giant cells

Karyotype

Human hypotetraploid karyotype with 3.5% polyploidy - 81(77-82)<4n>XXYY, -2, -7, -12, +13, -14, -14, -16, -18, -19, -22, +1-3mar, add(9)(q1)x2, der(9)del(9)(p21.2)t(9;22)(q34;q11)x2, der(11)t(11;9;22)(p15;q34;q11)x2, add(17)(p13)x1-2, der(22)t(9;22)(q34;q

Quality Control

Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD4 -, CD13 +, CD19 -, CD30 +, CD33 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 8 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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