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E2A Breakapart Probe
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Cat.No.
FHPC-051
Description
Translocations involving the E2A gene have been characterised in childhood B-ALL. At present, there are two partner genes, PBX1 and HLF (on chromosomes 1 and 17 respectively) which become fused to E2A as a result of the t(1;19) and t(17;19) translocations forming the E2A/PBX1 and E2A/HLF fusion proteins respectively. The former is more common, being present in about 5% of paediatric ALLs whilst the other is present in some 1%. Both are associated with poor outcome. Detection of the t(1;19) is best carried out using molecular methods such as FISH.
Size
5 Tests, 10 Tests
Label
Red/Green
Specificity
Human
Locus
t(1;19)/t(17;19)
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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