CEP X/Y Probe

FHPC-029

The CEP X/Y DNA Probe Kit may be used as an adjunct to standard karotyping to evaluate engraftment success in recipients of sex mismatched bone-marrow transplantation by determining the proportion of XX and XY donor cells. Following transplantation, an assessment of the proportion of cells belonging to the donor and to the recipient can be used to evaluate engraftment, detect the presence of clonal neoplasms and determine syndrome recurrence. This probe kit offers a limit of detection of 1% through a combination of CEP X and CEP Y fluorescently labeled DNA probes for specific regions of chromosome X and chromosome Y, respectively. This probe provides rapid (results in 3 hours or less) and accurate identification of the genetic sex of the bone marrow cells. Bone-marrow transplantation is a critical therapeutic strategy in the management of hematologic malignancies, such as: Chronic Myelogenous Leukemia (CML), Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Myeloproliferative Disorder (MPD), Chronic Lymphocytic, Leukemia (CLL), Myelodysplastic Syndrome (MDS), Other hematologic disorders not otherwise specified (HDNOS)

20 Tests

Red/Green

Human

Xp11.1-q11.1 Alpha Satellite DNA/Yq12 Satellite III

For Research Use Only. Not for use in diagnostic procedures.

Store at minus 20 centigrade

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.