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CDKN2A/CEP 10 Probe
- Specification
Cat.No.
FONC-027
Description
Alterations of the 9p21 locus including the tumor suppressor gene CDKN2A (p16) are implicated in different Meningiomas and Gliomas. Studies support the association of CDKN2A homozygous deletion with malignant progression and suggest that it is a marker of anaplastic oligodendrogliomas.
The CDKN2A/CEP 9 Probes have been used in several cytogenetic studies to detect losses of the CDKN2A gene. Using this probe set as well as other relevant markers (e.g. p53, RB1, 1p36, 19q13, all Vysis FISH probes), Kramar et al. investigated 82 samples with histolgically confirmed glial tumors.
The CDKN2A/CEP 9 Probes have been used in several cytogenetic studies to detect losses of the CDKN2A gene. Using this probe set as well as other relevant markers (e.g. p53, RB1, 1p36, 19q13, all Vysis FISH probes), Kramar et al. investigated 82 samples with histolgically confirmed glial tumors.
Size
20 Tests
Label
Red/Green
Specificity
Human
Locus
9p21/9p11-q11
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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