A2780/cis

Cat.No.: CSC-C9492J

Species: Human

Source: Reproductive: Ovary

Morphology: Epithelial

Culture Properties: Adherent

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Cat.No.

CSC-C9492J

Description

This cisplatin-resistant cell line has been developed by chronic exposure of the parent cisplatin-sensitive A2780 cell line to increasing concentrations of cisplatin. A2780cis is cross-resistant to melphalan, adriamycin and irradiation. An increased ability to repair DNA damage as well as cytogenetic abnormalities has been observed. In order to retain resistance cisplatinum has to be added to the media for every passage. In addition to this matched pair of drug-sensitive/resistant cell lines an adriamycin-resistant cell line, A2780adr, has been isolated from the same parental line A2780.

Species

Human

Source

Reproductive: Ovary

Recommended Medium

RPMI 1640 + 2mM Glutamine + 1μM cisplatinum + 10% Fetal Bovine Serum (FBS) .

Culture Properties

Adherent

Morphology

Epithelial

Storage and Shipping

Creative Bioarray ships frozen cells on dry ice. On receipt, immediately transfer frozen cells to liquid nitrogen (-180 °C) until ready for experimental use.
Never can cryopreserved cells be kept at -20 °C.

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

What are the common characteristics of ovarian cancer cells?

Ovarian cancer cells often exhibit characteristics such as uncontrolled growth, the ability to invade nearby tissues, resistance to cell death (apoptosis), and the potential to spread (metastasize) to other organs.

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Average Rating: 4.0 | 1 Scientist has reviewed this product

Good

The product was surprisingly frozen well, with minimal cell death observed during storage.

21 May 2023

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