A2780/ADR

Cat.No.: CSC-C9487J

Species: Human

Source: Reproductive: Ovary

Morphology: Epithelial

Culture Properties: Adherent

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Cat.No.

CSC-C9487J

Description

The adriamycin-resistant cell line A2780ADR has been developed by exposure of the parent A2780 cell line to adriamycin. A2780ADR is cross-resistant to melphalan and vinblastine. To retain resistance adriamycin has to be added to the media. The cells grow as a monolayer and in suspension in spinner cultures and are tumourigenic in immune deficient mice. Together with the cisplatin-resistant variant A2780cis these lines only differ in their exposure to a single drug and should facilitate the search for molecular changes responsible for the expression of pleiotropic drug resistance in human ovarian cancer.

Species

Human

Source

Reproductive: Ovary

Recommended Medium

RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS); treatment with 10E-7 M adriamycin at least once a week.

Culture Properties

Adherent

Morphology

Epithelial

Storage and Shipping

Creative Bioarray ships frozen cells on dry ice. On receipt, immediately transfer frozen cells to liquid nitrogen (-180 °C) until ready for experimental use.
Never can cryopreserved cells be kept at -20 °C.

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Which 3 types of cells are found in the ovary?

Although various family members are expressed by the major ovarian cell types (i.e., oocytes, granulosa cells, and thecal cells), many of their effects center on the control of granulosa cell growth and differentiation, both of which affect folliculogenesis and oocyte development.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

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The resources from Creative Bioarray have been extremely helpful in optimizing our experimental techniques and ensuring consistent and reliable results.

12 Mar 2023

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OC 316

Description: Species: human female 60 years old;
Tissue: ovary;
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G3 FIGO stage IV (pleural metastasis);
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EFO-27

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COLO-704

Description: Established from the ascites fluid stemming from the colon metastasis of a 46-year-old white woman with ovarian adenocarcinoma in 1986

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EFO-21

Description: Established from the ascitic fluid of a 56-year-old Caucasian woman with dedifferentiated serous cystadenocarcinoma of the ovary in 1979

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FU-OV-1

Description: Established post-hysterectomy from the tumor tissue of a 65-year-old Japanese woman with malignant ovarian carcinoma (stage: FIGO IIIc; histology: poorly differentiated serous papillary adenocarcinoma) in 1989

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Caov-3

Description: The cells are distributed for research purposes only. The culture condition is 37℃，95% air, carbon dioxide (CO2), complete growth medium supplemented with 5% (v/v) DMSO

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For research use only. Not for any other purpose.