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1p1q FISH Probe
- Specification
Cat.No.
FONC-141
Description
1p1q FISH Probe is specifically designed to detect deletions and amplifications in the p and q arms of chromosome 1. This probe is labeled in vibrant colors for optimal visualization, and we offer customization options to meet your specific research needs.
Chromosome 1 is the largest human chromosome and contains a diverse array of genes that are crucial for various biological functions, including cell cycle regulation, signal transduction, and immune response. Alterations in chromosome 1, particularly in the 1p and 1q regions, have been associated with several malignancies, including breast cancer, glioblastoma, and hematological disorders. These genetic changes can lead to the dysregulation of oncogenes and tumor suppressor genes, contributing to tumorigenesis.
Clinical Relevance: The detection of deletions and amplifications in the 1p and 1q regions is essential for the diagnosis and characterization of various cancers. For instance, 1p deletions are often linked to poor prognosis in certain types of gliomas, while 1q amplifications may indicate aggressive disease behavior in breast cancer. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform treatment strategies, allowing for more personalized therapeutic approaches.
Utilizing our 1p1q FISH Probe enables researchers to gain a comprehensive understanding of the genetic landscape of tumors, facilitating the identification of potential therapeutic targets and improving patient management.
Chromosome 1 is the largest human chromosome and contains a diverse array of genes that are crucial for various biological functions, including cell cycle regulation, signal transduction, and immune response. Alterations in chromosome 1, particularly in the 1p and 1q regions, have been associated with several malignancies, including breast cancer, glioblastoma, and hematological disorders. These genetic changes can lead to the dysregulation of oncogenes and tumor suppressor genes, contributing to tumorigenesis.
Clinical Relevance: The detection of deletions and amplifications in the 1p and 1q regions is essential for the diagnosis and characterization of various cancers. For instance, 1p deletions are often linked to poor prognosis in certain types of gliomas, while 1q amplifications may indicate aggressive disease behavior in breast cancer. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform treatment strategies, allowing for more personalized therapeutic approaches.
Utilizing our 1p1q FISH Probe enables researchers to gain a comprehensive understanding of the genetic landscape of tumors, facilitating the identification of potential therapeutic targets and improving patient management.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
1p32.3/1q21.3
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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