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MES-SA/Dx-5

Cat.No.: CSC-C9508J

Species: Human

Source: Reproductive: Uterus

Morphology: Epithelial

Culture Properties: Adherent

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Cat.No.
CSC-C9508J
Description
The multi drug-resistant cell line MES-SA/Dx5 was derived from the human uterine sarcoma cell line MES-SA which was originally obtained from a tumour from a 56-year-old Caucasian female at the time of hysterectomy. The Dx5 variant exhibits a 100-fold resistance to doxorubicin and has a reported doubling time of 30 hours. The two additional marker chromosomes indicate clonal selection during drug selection. MES-SA/Dx-5 cells exhibit marked cross-resistance to a number of chemotherapeutic agents (including daunorubicin, dactinomycin, vincristine, taxol, colchicine) and moderate cross-resistance to mitomycin C and melphalan. Cross resistance to bleomycin, cisplatin, carmustine, 5-fluorouracil or methotrexate was not observed.
Species
Human
Source
Reproductive: Uterus
Recommended Medium
McCoy's 5a + 2mM Glutamine + 10% Fetal Bovine Serum (FBS)
Culture Properties
Adherent
Morphology
Epithelial
Storage and Shipping
Creative Bioarray ships frozen cells on dry ice. On receipt, immediately transfer frozen cells to liquid nitrogen (-180 °C) until ready for experimental use.
Never can cryopreserved cells be kept at -20 °C.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
What are the challenges in predicting and preventing lymph node metastasis?

Challenges include the complex nature of tumor metastasis, variability in individual patient responses, and the need to identify reliable predictive markers.

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Average Rating: 4.0    |    1 Scientist has reviewed this product

Exceptional quality

The cell biology products greatly enhanced our research, delivering high-quality and consistent results across various experiments.

09 Feb 2023


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