COR-L23/R23-

Cat.No.: CSC-C9496J

Species: Human

Source: Lung

Morphology: Epithelial

Culture Properties: Adherent

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Cat.No.

CSC-C9496J

Description

The revertant lung cancer cell line COR-L23/R23- was generated by growing the doxorubicin-selected, resistant variant COR-L23/R without drug exposure for 24-28 weeks. The cell line, also known as COR-L23/Rev, overexpresses multidrug resistance -associated protein (MRP), but to a lesser extent than the parent line. It was shown that the cell line has the ability to recover quickly, similar levels of MRP expression and resistance as COR-L23/R after a transient exposure to the MDR-drugs doxorubicin and vincristine.

Species

Human

Source

Lung

Recommended Medium

RPMI 1640 +2mM Glutamine + 10% Fetal Bovine Serum (FBS)

Culture Properties

Adherent

Morphology

Epithelial

Storage and Shipping

Creative Bioarray ships frozen cells on dry ice. On receipt, immediately transfer frozen cells to liquid nitrogen (-180 °C) until ready for experimental use.
Never can cryopreserved cells be kept at -20 °C.

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Why is MTT assay preferred?

The MTT assay is a sensitive and reliable indicator of cellular metabolic activity and is preferred over the other methods measuring this end-point like the ATP and 3H-thymidine incorporation assay, the latter employing radioactivity.

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Average Rating: 4.0 | 1 Scientist has reviewed this product

Accurate description

I was helped a lot by the detailed instructions and directions for each cellular product.

01 July 2023

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For research use only. Not for any other purpose.