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KANSL1 FISH Probe
- Specification
Cat.No.
FONC-144
Description
KANSL1 FISH Probe is specifically designed to detect amplifications and deletions of the KANSL1 gene. This probe is labeled in vibrant orange for optimal visualization, and we offer customization options to meet your specific research needs.
The KANSL1 (KAT8 regulatory NSL complex subunit 1) gene is located on chromosome 17 and plays a crucial role in chromatin remodeling and gene expression regulation. Alterations in KANSL1 have been associated with various developmental disorders and cancers. Notably, KANSL1 deletions are linked to KANSL1 syndrome, which is characterized by intellectual disability, developmental delays, and distinctive facial features.
Clinical Relevance: Detecting KANSL1 amplifications and deletions is essential for understanding the genetic basis of associated disorders and malignancies. In cancer, KANSL1 dysregulation can contribute to tumorigenesis by affecting cellular proliferation and differentiation. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform treatment strategies, particularly in cancers where KANSL1 plays a significant role.
Utilizing our KANSL1 FISH Probe allows researchers to gain a deeper understanding of the genetic landscape associated with KANSL1 alterations. This probe is an invaluable tool for advancing research in genetics and oncology, facilitating the identification of potential therapeutic targets and improving patient management.
The KANSL1 (KAT8 regulatory NSL complex subunit 1) gene is located on chromosome 17 and plays a crucial role in chromatin remodeling and gene expression regulation. Alterations in KANSL1 have been associated with various developmental disorders and cancers. Notably, KANSL1 deletions are linked to KANSL1 syndrome, which is characterized by intellectual disability, developmental delays, and distinctive facial features.
Clinical Relevance: Detecting KANSL1 amplifications and deletions is essential for understanding the genetic basis of associated disorders and malignancies. In cancer, KANSL1 dysregulation can contribute to tumorigenesis by affecting cellular proliferation and differentiation. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform treatment strategies, particularly in cancers where KANSL1 plays a significant role.
Utilizing our KANSL1 FISH Probe allows researchers to gain a deeper understanding of the genetic landscape associated with KANSL1 alterations. This probe is an invaluable tool for advancing research in genetics and oncology, facilitating the identification of potential therapeutic targets and improving patient management.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
17q21.31
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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