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Human iPSC-derived renal proximal tubular cells
- Specification
Cat.No.
CSC-00833L
Description
Human iPSC-Derived Renal Proximal Tubular Cells are derived from integration-free iPSCs of a healthy donor and have been differentiated through the up-regulation of specific signalling pathways. To support the growth and maintenance of Human iPSC-Derived Renal Proximal Tubular Cells, we offer our Renal Epithelial Cell Culture Medium which is fully supplemented with hormones and recombinant growth factors that promote optimal growth. Our iPSC-Derived Renal Proximal Tubular Cells express critical functional markers, along with epithelial and renal cell markers. These include the important phosphate transporter, SLC34A1, the organic ion transporter crucial for baso-lateral uptake of organic anions, OAT1 and the apical glucose transporter SGLT2, key in glucose reabsorption from the glomerular filtrate. These cells provide a physiologically relevant model for investigating glucose uptake in diabetes, the transportation of drugs and endogenous metabolites, and detecting nephrotoxicity.
Species
Human
Recommended Medium
Human iPSC-derived Renal Epithelial Cell Culture Media
Applications
For Research Use Only
Shipping
Dry Ice
Storage and Shipping
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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