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BRCA2 FISH Probe
- Specification
Cat.No.
FONC-124
Description
BRCA2 FISH Probe is specifically designed to detect amplifications and deletions of the BRCA2 gene, a critical component in the maintenance of genomic stability. This probe is available with vibrant orange labeling for enhanced visualization, and we offer customization options to meet your specific research needs.
BRCA2 (Breast Cancer 2) is a well-known tumor suppressor gene that plays a vital role in DNA repair through homologous recombination. Mutations and structural alterations in BRCA2 are strongly associated with hereditary breast and ovarian cancers, making it a key target for genetic testing and cancer research. Amplifications or deletions of BRCA2 can lead to impaired DNA repair mechanisms, contributing to tumorigenesis and cancer progression.
Clinical Relevance: The detection of BRCA2 amplifications and deletions is crucial for understanding the genetic basis of breast and ovarian cancers. Identifying these alterations can aid in risk assessment, guide treatment decisions, and inform targeted therapies, such as PARP inhibitors, which are particularly effective in tumors with BRCA2 deficiencies.
Our BRCA2 FISH Probe is an essential tool for researchers dedicated to advancing cancer genetics and improving patient outcomes through personalized medicine.
BRCA2 (Breast Cancer 2) is a well-known tumor suppressor gene that plays a vital role in DNA repair through homologous recombination. Mutations and structural alterations in BRCA2 are strongly associated with hereditary breast and ovarian cancers, making it a key target for genetic testing and cancer research. Amplifications or deletions of BRCA2 can lead to impaired DNA repair mechanisms, contributing to tumorigenesis and cancer progression.
Clinical Relevance: The detection of BRCA2 amplifications and deletions is crucial for understanding the genetic basis of breast and ovarian cancers. Identifying these alterations can aid in risk assessment, guide treatment decisions, and inform targeted therapies, such as PARP inhibitors, which are particularly effective in tumors with BRCA2 deficiencies.
Our BRCA2 FISH Probe is an essential tool for researchers dedicated to advancing cancer genetics and improving patient outcomes through personalized medicine.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
13q13.1
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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