ZNF217 Amplification Probe | Creative Bioarray

Cat.No.

FONC-117

Description

The Zinc Finger protein 217 gene (ZNF217) functions as a transcription repressor for a variety of genes. It is a strong oncogene candidate which drives the 20q13.2 amplification in breast cancer, ovarian cancer and other tumours and is associated with aggressive tumour behaviour. It has been shown that the silencing of ZNF217 inhibits ovarian cancer cell growth and the invasive ability in cancer cell lines.
The ZNF217 gene is a candidate oncogene suggested to play a key role during neoplastic transformation. ZNF217 is located at 20q13, a region that is frequently amplified in a variety of tumor types.1-6 Amplification of ZNF217 in breast cancer is associated with aggressive tumor behaviour.

Size

5 Tests, 10 Tests. 20 Tests

Label

Red/Green/Gold

Specificity

Human

Locus

20q13.2

Usage

For Research Use Only. Not for use in diagnostic procedures.

Storage

Store at minus 20 centigrade

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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