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MYC Probe Kit
- Specification
Cat.No.
FONC-082
Description
The MYC (C-MYC) oncogene has been reported to be amplified in >20% of breast carcinoma and various other malignancies and is a prognostic factor for breast cancer. FISH is a rapid and reproducible method that allows the accurate measurement of the level of oncogene amplification within interphase nuclei in human tumors. This probe may be used to determine the MYC copy number or as a general purpose probe for the 8q24 region.
Used this Probe to investigate co-amplification of the MYC and HER2 genes in 214 consecutive breast cancers. For detecting lung cancer, Sokolava et al. compared a FISH-based assay, that included Vysis LSI MYC, to conventional cytology in 74 bronchial washing specimens, and achieved significantly higher sensitivity with the FISH assay (82% vers. 54%).
Used this Probe to investigate co-amplification of the MYC and HER2 genes in 214 consecutive breast cancers. For detecting lung cancer, Sokolava et al. compared a FISH-based assay, that included Vysis LSI MYC, to conventional cytology in 74 bronchial washing specimens, and achieved significantly higher sensitivity with the FISH assay (82% vers. 54%).
Size
20 Tests
Label
Red/Green/Gold
Locus
8q24
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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