ETV6/RUNX1 Dual Fusion Probe | Creative Bioarray

Cat.No.

FHPC-055

Description

The ETV6/RUNX1 Dual Fusion Probe is intended to detect the t(12;21)(p13;q22) translocation between the ETV6 gene and the RUNX1 gene using the fluorescence in situ hybridization (FISH) technique. The t(12;21)(p13;q22) chromosomal translocation is the most common chromosomal rearrangement in childhood acute lymphocytic leukemia (ALL). Although not detectable by classical cytogenetics,1 the t(12;21) resulting in the fusion of the 5' section of the ETV6 (TEL) gene on chromosome 12p13 to almost the entire RUNX1 (AML1) gene located on chromosome 21q22 occurs in about 25% of childhood ALL.2 The Vysis ETV6/RUNX1 DF FISH Probe Kit uses a dual-color, dual-fusion probe design to detect the t(12;21) by fluorescence in situ hybridization.

Size

20 Tests

Label

Red/Green

Specificity

Human

Locus

12p13/21q22

Usage

For Research Use Only. Not for use in diagnostic procedures.

Storage

Store at minus 20 centigrade

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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