BLUE-1

Cat.No.: CSC-C0597

Species: Human

Source: bone marrow

Morphology: round cells growing singly or in clumps in suspension

Culture Properties: suspension

Inquire for Price

Specification
Q & A
Customer Review

Cat.No.

CSC-C0597

Description

Established from the bone marrow of a 29-year-old Caucasian man with Burkitt lymphoma in second relapse following combined chemotherapy and radiotherapy in 2004; cells are described to carry t(6;20)(q15;q11.2) leading to BACH2-BCL2L1 fusion gene

Species

Human

Source

bone marrow

Recommended Medium

80% RPMI-1640 + 20% h.i. FBS

Culture Properties

suspension

Morphology

round cells growing singly or in clumps in suspension

Karyotype

Human hyperdiploid karyotype; 53(49-53)<2n>XY, +6, +13, +16, +20, +20, +20, +21, t(6;20)(q15;q11.2), der(6)t(6;20)(q15;q11.2), t(8;14)(q24;q32), der(20)del(20)(p12.2p13.2)t(6;20)(q15;q11.2)t(6;11)(q16;p13)x2; carries t(8;14) effecting IGH@-MYC juxtapositi

Quality Control

Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD13 -, CD19 +, CD20 -, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 -, CD138 -, HLA-DR +, sm/cyIgG +, sm/cyIgM -, cykappa -, cylambda +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HT

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 10-15 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Can tumors be polyclonal?

Polyclonal tumors might become established at a higher frequency than monoclonal tumors because interactions between initiated clones alter the microenvironment. Molecule-mediating interactions within a polyclonal tumor might also be critical for tumor progression.

Ask a Question