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AML1/ETO Translocation, Dual Fusion Probe
- Specification
Cat.No.
FHPC-006
Description
The AML/ETO t(8;21)(q21;q22) specific DNA Probe is optimized to detect the reciprocal translocation t(8;21) in a Dual-Color, Dual-Fusion.
AML1 is fused with ETO in the t(8;21)(q21;q22) translocation.Overall, 7% of AML cases demonstrate the abnormality. Three-way variants of this rearrangement and the t(3;21) (AML1/EVI1) show that juxtaposition of AML1 to the derivative chromosome is consistent and therefore the critical rearrangement.
AML1 is fused with ETO in the t(8;21)(q21;q22) translocation.Overall, 7% of AML cases demonstrate the abnormality. Three-way variants of this rearrangement and the t(3;21) (AML1/EVI1) show that juxtaposition of AML1 to the derivative chromosome is consistent and therefore the critical rearrangement.
Size
5 Tests, 10 Tests
Label
Red/Green
Locus
8q21/21q22
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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