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13q Tri-color FISH Probe
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Loss of heterozygosity on chromosome 13q is one of the most common genetic alterations in hepatocellular carcinoma (HCC) and might be involved in liver cancer development through inactivation of tumour suppressor genes. Variable combinations of deletions of the RB1, LAMP1 and or DS13S319 genes are common in a variety of hematological malignancies including chronic lymphocytic leukemia (CLL), acute myelocytic leukemia (AML) and MM1,2,3.
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