KU-812

Cat.No.: CSC-C0426

Species: Homo sapiens, human

Source: Blood

Morphology: Lymphoblast

Culture Properties: Suspension

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Cat.No.

CSC-C0426

Description

Established from the peripheral blood of a 38-year-old man with chronic myeloid leukemia (CML) in myeloid blast crisis; described to express basophilic features and to carry t(9;22) leading to BCR-ABL1 e14-a2 (b3-a2) fusion gene.

Species

Homo sapiens, human

Source

Blood

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

Suspension

Morphology

Lymphoblast

STR DNA Profile

Amelogenin: X,Y
CSF1PO: 12,13
D13S317: 8
D16S539: 9
D18S51: 13
D21S11: 30,31,2
D3S1358: 15
D5S818: 10
D7S820: 12
D8S1179: 11,15
FGA: 22,24
Penta D: 12
Penta E: 5,19
THO1: 9
TPOX: 12
vWA: 15
D18S51: 13
Penta E: 14,16
Penta D: 11,13
D8S1179: 10
FGA:

Karyotype

58, XY, t(9;22)(q34;q11), i(17q), +1, +4, +6, +6, +8, +der(9)t(9;22), + der(9)t(9;22), +der(11)q(11), +14, +15, +19, +21, +21, -9

Applications

This cell line can be used in chromosome and tumourigenicity studies.

Disease

Chronic myelogenous leukemia

Quality Control

Tests for mycoplasma, bacteria and fungi were negative

Storage and Shipping

liquid nitrogen vapor phase

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

What is fluorescence in situ hybridization in cancer?

FISH can be used to identify where a specific gene is located on a chromosome, how many copies of the gene are present, and any chromosomal abnormalities. It is used to help diagnose diseases, such as cancer and help plan treatment. Also called FISH.

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